甲磺酸罗哌卡因 CAS: 854056-07-8原料供应发货实验室定制
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| 中文名 | 甲磺酸罗哌卡因 |
| 英文名 | ropivacainemesylate |
| 别名 | 甲磺酸罗哌卡因 罗哌卡因甲磺酸盐 甲磺酸罗哌卡因中间体 s-罗哌卡因甲磺酸盐 甲磺酸罗哌卡因854056-07-8 n-(2,6-二甲基苯基)-1-丙基哌啶-2-甲酰胺甲磺酸盐 n-(2,6-二甲基苯基)-1-正丙基哌啶-2-甲酰胺甲磺酸盐 (s)-n-(2,6-二甲基苯基)-1-丙基-2-哌啶酰胺甲磺酸盐 s-(-)-n-(2,6-二甲基苯基)-1-丙基-2-哌啶甲酰胺甲磺酸盐 |
| 英文别名 | ropivacainemesylate ropivacainemesylate s-ropivacainemesylate (s)-ropivacainemesilate ropivacainemesylate api ropivacaine mesylate injection tianfuchem--854056-07-8--ropivacaine mesylate in stock (s)-n-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamidemethanesulfonate (2s)-n-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamidemonomethanesulfonate ropivacaine mesylate(2s)-n-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamidemonomethanesulfonate |
| cas | 854056-07-8 |
| einecs | 264-407-7 |
| 化学式 | c18h30n2o4s |
| 分子量 | 370.51 |
| inchi | inchi=1/c17h26n2o.ch4o3s/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3;1-5(2,3)4/h7-9,15h,4-6,10-12h2,1-3h3,(h,18,20);1h3,(h,2,3,4)/t15-;/m0./s1 |
| 体内研究 | epidural administration of ropivacaine mesylate effectively blocksneuropathic pain (both mechanical allodynia and heat hyperalgesia)without induction of analgesic tolerance and significantly delaysthe development of neuropathic pain produced by peripheral nerveinjury. ropivacaine mesylate inhibits pressure-induced increases infiltration coefficient (kf) without affecting pulmonary arterypressure (ppa), pulmonary capillary pressures (ppc), and zonalcharacteristics (zc). ropivacaine mesylate preventspressure-induced lung edema and associated hyperpermeability asevidence by maintaining pao2, lung wet-to-dry ratio and plasmavolume in levels similar to sham rats. ropivacaine mesylateinhibits pressure-induced no production as evidenced by decreasedlung nitro-tyrosine content when compared to hypertensive lungs.animal model: adult sprague-dawley rats (300-400g) dosage: 1 μmadministration: infusion (added to the perfusate reservoir) result:attenuated pressure-dependent increases in filtration coefficient(k f ). |
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