CAS101-20-2 EINECS202-924-1化学式C13H9Cl3N2O 分子量315.58InChIInChI=1/C13H10Cl2N2O/c14-11-7-6-10(8-12(11)15)17-13(18)16-9-4-2-1-3-5-9/h1-8H,(H2,16,17,18)InChIKeyICUTUKXCWN密度1.5732 (rough estimate)熔点254-256 °C (lit.)沸点344.2±42.0 °C(Predicted)闪点150°C蒸汽压<0.1 mm Hg ( 25 °C)溶解度甲醇: 可溶折射率1.6300 (estimate)酸度系数12.77±0.70(Predicted)存储条件Sealed in dry,Room Temperature稳定性稳定。可燃。与强氧化剂强碱不相容。外观整洁颜色Fine platesMerck14,9654物化性质白色粉末。MDL号MFCD00013254体外研究Triclocarban (300 nM) potentiates the cytotoxicity of 300 µM H 2 O 2 in rat thymocytes. Triclocarban (300 nM) does not increase the population of death cells, it facilitates the process of cell death induced by H 2 O 2 , resulting in further increase in the population of dead cells. Triclocarban exertes estrogenic activities by inducing luciferase activities in an ER reporter gene assay, promoting the proliferation of the MCF-7 cells, up-regulating the expression of pS2 and down-regulating ERα expression at both the mRNA and protein levels in the MCF-7 cells.体内研究Triclocarban is absorbed significantly from soap used during showering in human subjects and that its C max in their whole blood ranges from 23 nM to 530 nM. Gestational triclocarban exposure does not affect the ability of dams to carry offspring to term but triclocarban exposure during lactation has adverse conse on the survival of offspring.危险品标志N - 危害环境的物品 风险术语50/53 - 对水生生物有极高毒性，可能对水体环境产生长期不良影响。 安全术语S60 - 该物质及其容器须作为危险性废料处置。 S61 - 避免释放至环境中。参考特别说明/安全数据说明书。 危险品运输编号UN 3077 9/PG 3WGK Germany2RTECSFE1250000海关编号38220090Hazard Class9Packing GroupIII
