蛙皮素 97% 单瓶试剂配送 贯穿式服务 可开专票 31362-50-2

CAS31362-50-2
化学式C71H110N24O18S
分子量1619.85密度1.50±0.1 g/cm3(Predicted)溶解度0.05 M乙酸: 20mg/ml，澄清，无色酸度系数13.04±0.46(Predicted)存储条件Keep in dark place,Inert atmosphere,Store in freezer, under -20°C外观粉末Merck13,体外研究Bombesin is a tetradecapeptide with a COOH terminus ending in Gly-His-Leu-Met-NH2 and subse is shown to closely resemble two mammalian bombesin -related peptides, gastrin-releasing peptide (GRP) and neuromedin B (NMB). Bombesin is found to have stimulatory effects upon gastric and pancreatic secretions, release of gastrointestinal hormones, gallbladder contraction and bronchoconstriction. It is present in amphibian gastric endocrine cells, avian proventriculus endocrine cells and avian brain. In mammals it is present mainly in nerve cells and fibers. The only mammalian endocrine cell shown to date to have bombesin is the P-cell in fetal lung. Bombesin is also found in mammalian brain, with its highest concentration in the hypothalamus. Bombesin is shown to be a potent mitogen for Swiss 3T3 cells. In the presence of a low concentration (3.5%) of serum, bombesin stimulates 3T3 cell proliferation. In serum-free medium, bombesin induces DNA synthesis in the absence of any other added growth factor (IC 50 =1 nM).31362-50-2 - 简介

蛙皮素是一种生物活性肽类物质，主要存在于部分无尾两栖动物（如蛙类）的皮肤腺体中。它具有多种生物活性，包括抗菌、抗病毒、抗肿瘤以及调节免疫系统等作用。
蛙皮素的用途很广泛。蛙皮素也被用于研究肿瘤治疗，因为它可以抑制肿瘤细胞的生长和扩散。蛙皮素还被应用于皮肤保养产品中，具有修复和抗衰老的功能。
蛙皮素的制法通常是通过提取蛙类皮肤组织并通过化学方法得到。一般来说，提取过程包括研磨皮肤组织、加入溶剂提取活性成分，然后通过蒸发和干燥等步骤得到纯化的蛙皮素。
蛙皮素的安全性，在合理使用的情况下，它通常是安全的。具体的安全信息和剂量需要根据具体的蛙皮素类型和使用情况进行评估。