中文名熊去氧胆酸
英文名ursodeoxycholic acid
别名熊脱氧胆酸
熊去氧胆酸
乌索脱氧胆酸
乌索去氧胆酸
熊果去氧胆酸
3alpha,7beta-二羟基-5beta-胆甾烷-24-酸
英文别名udca
ursodiol
ursodiol
tauroursodiol
ursodeoxycholic acid
ursodeoxycholoc acid
ursodeoxycholic acid
ursodesoxycholic acid
urosodeoxycholic acid
3,7-dihydroxycholan-24-oic acid
ursodeoxycholic acid(micronized)
2-(2-methyl-5-nitro-1h-imidazol-1-yl)ethanol
3alpha,7beta-dihydroxy-6beta-cholan-24-oic acid
(3alpha,5beta,7beta)-3,7-dihydroxycholan-24-oate
(3alpha,5alpha,7beta)-3,7-dihydroxycholan-24-oate
(3alpha,5beta,7beta)-3,7-dihydroxycholan-24-oic acid
(3alpha,5beta,7alpha)-3,7-dihydroxycholan-24-oic acid
(3alpha,5beta,7beta,8xi,9xi,14xi)-3,7-dihydroxycholan-24-oicacid
(4r)-4-[(3r,5s,8r,9s,10s,13r,14s,17r)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]pentanoicacid
(4r)-4-[(3r,5s,7s,9s,10s,13r,14s,17r)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]pentanoicacid
cas128-13-2
einecs204-879-3化学式c24h40o4
分子量392.57inchiinchi=1/c24h40o4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26h,4-13h2,1-3h3,(h,27,28)/p-1/t14-,15-,16-,17-,18+,19+,20+,22+,23+,24-/m1/s1inchikeyrudatboh-n密度0.9985 (rough estimate)熔点203-204 °c (lit.)沸点437.26°c (rough estimate)比旋光度60 º (c=2, etoh)闪点9℃水溶性practically insoluble蒸汽压0mmhg at 25°c溶解度乙醇: 50mg/ml，澄清折射率60.5 ° (c=2, etoh)酸度系数pka 5.04±0.04(h2ot = 25.0±0.1i = 0.00)(approximate)存储条件2-8°c外观固体.粉末.颜色white - almost white.merck14,9889brn3219888物化性质本品为白色粉末；无臭，味苦。mp200-204℃。在乙醇和冰醋酸中易溶，在氢氧化钠试液中溶解，在氯仿中不溶。udca为cdca的同分异构体，其溶石作用强于cdca，无腹泻及肝脏毒性。udca能降低胆固醇的吸收，并能降低胆固醇的合成及胆汁中的胆固醇含量。另外，udca亦能降低伴刀豆蛋白a结合片段，该物质能促进胆汁结晶的形成，从而抑制结石的形成。udca和cdca联合使用，可增强各自单独使用的溶石作用，同时减轻副作用。两者联用主要用于治疗胆囊胆固醇结石，患者胆石与胆汁等密度或者胆石ct值低于75单位时，udca的溶石速度zui快。胆石症病人使用本品后，可增加外周血小板数量。mdl号mfcd00003680
盐酸奈必洛尔原料-多肽glp-1原料-睾酮激素甾体-南京辰瑞晟生物医药科技公司，
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仅供科研实验或出口
