枸橼酸托法替尼 托法替尼杂质43CAS: 540737-29-9原料药研发供应中间体

中文名枸橼酸托法替尼
英文名1-piperidinepropanenitrile,4-methyl-3-(methyl-7h-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-,(3r,4r)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
别名枸橼酸托法替尼
托法替尼杂质43
枸橼酸 托法替尼-13c-d3
(3r,4r)-托法替尼柠檬酸盐
tofacitinib citrate枸橼酸托法替尼
3-((3r,4r)-4-甲基-3-(甲基(7h-吡咯并[2,3-d]嘧啶-4-基)氨基)哌啶-1-基)-3-氧代丙腈枸橼酸盐
3-[(3r,4r)-4-甲基-3-[甲基(7h-吡咯并[2,3-d]嘧啶-4-基)氨基]-1-哌啶基]-3-氧代丙腈-2-羟基丙烷-1,2,3-三甲酸盐
英文别名xeljanz
cp690550-10
cp690500-10
tofacitinibcitrate
cp-690550 (tofacitinib citrate)
1-piperidinepropanenitrile,4-methyl-3-(methyl-7h-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-,(3r,4r)-, citrate
(3r,4r)-1-(cyanoacetyl)-4-methyl-n-methyl-n-1h-pyrrolo[2,3-d]pyrimidin-4-yl-3-piperidinamine2-hydroxy-1,2,3-propanetricarboxylate
(3r,4r)-4-methyl-3-(methyl-7h-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidinepropanenitrile2-hydroxy-1,2,3-propanetricarboxylate
cas540737-29-9
einecs638-826-4化学式c16h20n6o.c6h8o7
分子量504.497inchiinchi=1s/c16h20n6o.c6h8o7/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16;7-3(8)1-6(13,5(11)12)2-4(9)10/h4,7,10-11,13h,3,5,8-9h2,1-2h3,(h,18,19,20);13h,1-2h2,(h,7,8)(h,9,10)(h,11,12)/t11-,13+;/m1./s1inchikeysyikufdoyjfgb熔点201 °c (decomp)溶解度dmso: soluble5mg/ml (clear solution; warmed)存储条件room temp外观powder颜色white to beigemdl号mfcd11616529