详细介绍
中文名盐酸奥替尼啶
英文名n,n'-(decane-1,10-diyldi-1(4h)-pyridyl-4-ylidene)bis(octylammonium)dichloride
别名奥替尼啶杂质
盐酸奥替尼啶
奥替尼啶盐酸盐
奥克太啶盐酸盐
奥替尼定盐酸盐
奥替尼啶,奥克太啶
奥替尼啶 二盐酸盐
奥替尼啶 奥克太啶(双盐酸盐)
英文别名octenidinehcl
octenidinehydrochloride
ocenidinedihydrochloride
octenidinedihydrochloride
n'-(decane-1,10-diyldi-1(4h)-pyridyl-4-ylidene)bis(octylammonium)dichloride
n,n'-(decane-1,10-diyldipyridin-1-yl-4-ylidene)dioctan-1-aminedihydrochloride
n,n'-(decane-1,10-diyldi-1(4h)-pyridyl-4-ylidene)bis(octylammonium)dichloride
n,n'-(1,10-decanediyldi-1(4h)-pyridinyl-4-ylidene)bis-1-octanaminehydrochloride
n,n'-(1,10-decanediyldi-1(4h)-pyridinyl-4-ylidene)bis(1-octanamine)dihydrochloride
cas70775-75-6
einecs274-861-8化学式c36h64cl2n4
分子量623.82616inchiinchi=1/c36h62n4.2clh/c1-3-5-7-9-15-19-27-37-35-23-31-39(32-24-35)29-21-17-13-11-12-14-18-22-30-40-33-25-36(26-34-40)38-28-20-16-10-8-6-4-2;;/h23-26,31-34h,3-22,27-30h2,1-2h3;2*1hinchikeysmgtyjpmkxn密度1.046[at 20℃]熔点215-217℃沸点609.3°c at 760 mmhg闪点322.3°c水溶性14.2g/l at 20℃蒸汽压0pa at 25℃溶解度soluble in dimethyl sulfoxide and methanol.存储条件keep in dark place,inert atmosphere,room temperature稳定性hygroscopic外观solid颜色white to off-whitemerck14,6754体外研究octenidine concentrations of less than1.5 μm (0.94 μg/ml) causes agreater than 99% reduction of tested microbial population within 15min. staphylococcus epidermidis is the most susceptible of the testorganisms, and e. coli and c. albicans are the leastsusceptible.体内研究the antimicrobial activity of octenidine hydrochloride (oct) ismaintained when applied to the skin of the hands and feet ofcynomolgus monkeys. aqueous octenidine, at a concentration of 0.2to 1.6% reduces resident microflora populations from 90 to 99.98%.a significant reduction in plaque score is observed on the buccaltooth surfaces after daily topical application of 1% solutions ofoctenidine and chlorhexidine for 7 d; octenidine is more effectivethan chlorhexidine.
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