详细介绍
中文名米铂
英文名(sp-4-2)-[(1r,2r)-1,2-cyclohexanediamine-kappan,kappan'])bis(myristato-kappao)platinum(ii)
别名米铂
顺式-[双十四烷酸-(1r,2r)-1,2-环己二胺合铂(Ⅱ)]单水合物
顺[((1r,2r)-1,2-环己二胺-n,n')二(十四烷酰氧基)]合铂
英文别名dachpm
miripla
sm-11355
sm11355
smp-11355
miriplatin
dachpt(ii)(myr)2
[(1r,2r)-1,2-cyclohexanediamine]bis(myristato)platinum
(sp-4-2)-[(1r,2r)-1,2-cyclohexanediamine-kappan,kappan'])bis...
(sp-4-2)-[(1r,2r)-1,2-cyclohexanediamine-kappan,kappan'])bis(myristato-kappao)platinum
(sp-4-2)-[(1r,2r)-1,2-cyclohexanediamine-kappan,kappan'])bis(myristato-kappao)platinum(ii)
cas141977-79-9
化学式c34h66n2o4pt
分子量762溶解度10 mm in dmso存储条件keep in dark place,inert atmosphere,store in freezer, under-20°c体外研究miriplatin (sm-11355) suspended in lpd (miriplatin/lpd, 100 μg/ml)inhibits the growth of ah109a cells, forms platinum-dna adducts,and induces apoptosis.体内研究miriplatin (sm-11355) (0.02-0.4 mg/20 μl) in lipiodol reduces tumorgrowth rates in a dose dependent manner in rats bearing ah109atumor cells. miriplatin/lpd (400 μg/head) significantly reduces thegrowth of tumor in rats bearing ah109a cells.
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