中文名雄诺龙
英文名stanolone
别名雄诺龙
双氢睾酮
雄烯醇酮
加氢睾酮
二氢睾丸酮
雄诺龙(甾体)
雄诺龙 加氢睾酮
二氢睾酮(dht)
4,5Α-双氢睾酮
双氢睾酮(*终用户声明)
双氢睾酮(或称 雄诺龙)
英文别名stanolone
5a-androstan-3-on-17b-ol
17-hydroxyandrostan-3-one
17beta-hydroxy-3-androstanone
(17beta)-17-hydroxyandrostan-3-one
5a-androstan-3-one, 17beta-hydroxy-
17-beta-hydroxy-5-alpha-androstan-3-on
(3alpha,5alpha)-3-hydroxyandrostan-17-one
5α-androstan-17β-ol-3-one solution,100ppm
(5alpha,17beta)-17-hydroxy-androstan-3-one
(17beta)-3-oxoandrost-4-en-17-yl propanoate
(5-alpha,17-beta)-17-hydroxyandrostan-3-one
17-hydroxy-,(5-alpha,17-beta)-androstan-3-on
-(5-alpha,17-beta)-17-hydroxyandrostan-3-one
(5s,8r,9s,10s,13s,14s,17s)-17-hydroxy-10,13-dimethyltetradecahydro-1h-cyclopenta[a]phenanthren-3(2h)-one
(8r,9s,10s,13s,14s)-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
cas521-18-6
einecs208-307-3化学式c19h30o2
分子量290.45inchiinchi=1/c19h30o2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21h,3-11h2,1-2h3/t12?,14-,15-,16-,17-,18-,19-/m0/s1inchikeynvkawksa-n密度1.0320 (rough estimate)熔点178-183°c沸点372.52°c (rough estimate)比旋光度27 º闪点9℃水溶性344.3g/l(temperature not stated)蒸汽压1.5e-08mmhg at 25°c折射率1.4709 (estimate)酸度系数15.08±0.60(predicted)存储条件2-8°c外观neatmerck13,8872brn2056371产品用途雄激素类药体外研究在雄激素受体阳性的膀胱癌umuc3和tcc-sup细胞中，dihydrotestosterone(dht)可在mrna和蛋白水平上增加egfr和erbb2的表达。在ar阳性细胞中，dht还可上调egfr磷酸化水平及其下游蛋白akt（pakt）和erk1/2(perk)的磷酸化水平。体内研究dht可减轻sod1-g93a小鼠的肌萎缩症状并增加其体重。dht的处理增加了肌肉中胰岛素样生长因子1的表达，通过逆向轴浆运输发挥其肌肉营养性和神经营养性效果。其处理还减缓了神经肌肉接头处的去神经支配作用、以及减少轴突和运动神经元的丢失。dht处理的sod1-g93a小鼠改善了运动行为，生命期限也有所延长。
处理还减缓了神经肌肉接头处的去神经支配作用、以及减少轴突和运动神经元的丢失